They are a freak of nature and the greatest attraction in the circus: a magically gifted albino, a magnetic dwarf, a werewolf with superpowers and an electric dancer. When the Germans march into Rome in 1943 and their foster father Israel disappears without a trace while searching for an escape route, a bizarre odyssey begins for Cencio, Mario, Fulvio, and Matilde through the war-torn eternal city. The four of them must fight together for survival and hope to have found a new home in Circus Berlin. However, the circus director, a fanatical Nazi named Franz, pursues his own perverse plans and conducts grotesque human experiments.